What is the mechanism by which Fildena exerts its action on men?
Fildena is a famous drug of PDE-5 blockers category that exerts its therapeutic effect on the men by blocking the activity of PDE-5 enzymes, which is to disintegrate the cGMP available in the male genital area in tissues of corpus cavernosum. A man when gets aroused he liberates a chemical that has Vasodilator properties and this is Nitric Oxide (NO). The release of NO in men levels up the concentration of cGMP to excess. So, the two brings an instant relaxation and dilation of penile blood vessels so that the gush of blood disseminate in men penile shaft making the same erect & hard.
What is the accurate dosing regimen to consume Fildena 50 mg | 100 mg?
Fildena available in dosing 50 and 100mg is an oral formulation that patient can take an hour before with huge sum of water either in presence of absence of food in the stomach. Once the men take this dose he will attain this effect to duration next 4-5 hours. The gap of 24 hours is necessary between two consecutive dosing of Fildena. Men must avoid its intake by chewing, crushing or breaking the dose.
What are the malicious indications to dosing of Fildena 50 mg | 100 mg?
Fildena in men can develop some adverse effects such as queasiness, headache, indistinct vision, sore throat, nasal congestion, indigestion, back pain & stiffness, myalgia & tremor, painful and prolonged erection (Priapism).
What are the safety measures to be followed with Fildena 50 mg | 100 mg?
Some cautions are crucial to being followed, like mentioned below:
What are the Contradictions allied to Fildena therapy?
Use of Sildenafil is contradicted under some conditions:
What are the Interactions to Fildena therapy?
Alpha-blockers, Nitrate drugs like Isosorbides, Nitroglycerin, Azole antifungals, Macrolide antibiotics, H2 antagonists, HIV protease inhibitors, Barbiturates, Efavirenz, Phenytoin and Rifampin, show interaction with Sildenafil citrate enclosing Fildena medicines.
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